TB-500 (Thymosin Beta-4) 10MG

Name: TB-500 (Thymosin Beta-4) 10MG
SKU: 334
Availability: InStock

TB-500, a synthetic form of Thymosin Beta-4, supports blood vessel growth, reduces inflammation, and aids tissue repair. It’s particularly effective in healing muscle and tendon injuries and is of interest in anti-aging research.

Product Usage

This product is designated as a "Novelty Peptide" and is intended solely for specialized applications in controlled settings. It is not intended for any specific biological, therapeutic, or diagnostic use. All information provided on this website is for informational and educational purposes only and should not be construed as guidance for any particular application or usage.

What Is TB-500 (Thymosin Beta-4) 10MG?

TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4 (Tβ4). Thymosin Beta-4 is a highly conserved protein found in high concentrations in various tissues, including the spleen, thymus, and most cell types. TB-500 has gained significant attention in both medical research and sports due to its potential healing and regenerative properties. This 43-amino acid peptide plays crucial roles in tissue repair, cell migration, and angiogenesis, making it a promising candidate for various therapeutic applications.

Structure

Research Findings

Tissue Repair and Wound Healing: TB-500 has demonstrated significant potential in accelerating wound healing and tissue repair. Studies have shown its ability to promote cell migration, reduce inflammation, and enhance angiogenesis, leading to faster recovery in various types of injuries.
Cardiovascular Protection: Research has indicated that TB-500 may have cardioprotective effects. It has been shown to improve cardiac function after myocardial infarction by reducing inflammation, promoting cell survival, and activating epicardial progenitor cells.
Neuroprotection: TB-500 has exhibited neuroprotective properties in models of traumatic brain injury. It has been associated with reduced cortical lesion volume, improved functional recovery, and enhanced neurogenesis.
Anti-inflammatory Effects: The peptide has demonstrated potent anti-inflammatory properties across various disease models, potentially by down-regulating inflammatory mediators and up-regulating anti-inflammatory cytokines.
Angiogenesis Promotion: TB-500 has been observed to stimulate the formation of new blood vessels, which is crucial for tissue repair and regeneration.

Future Research Directions

Clinical Trials: While TB-500 has shown promising results in preclinical studies, more extensive human clinical trials are needed to establish its efficacy and safety for various conditions.
Mechanism of Action: Further research is required to fully elucidate the molecular mechanisms by which TB-500 exerts its diverse effects, particularly in different tissue types.
Combination Therapies: Exploring the potential synergistic effects of TB-500 with other therapeutic agents could open new avenues for treatment in various medical fields.
Long-term Effects: Studies investigating the long-term effects and potential side effects of TB-500 administration are necessary to ensure its safety for clinical use.
Delivery Methods: Research into optimal delivery methods and dosing regimens for different conditions could enhance the therapeutic potential of TB-500.

References

Goldstein, A.L., et al. (2012). "Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications." Expert Opinion on Biological Therapy, 12(1), 37-51. [Online].
Available: https://pubmed.ncbi.nlm.nih.gov/22074294/
Philp, D., et al. (2003). "Thymosin β4 promotes angiogenesis, wound healing, and hair follicle development." Mechanisms of Development, 120(12), 1335-1347. [Online].
Available: https://pubmed.ncbi.nlm.nih.gov/14623443/
Sosne, G., et al. (2007). "Thymosin beta 4 promotes corneal wound healing and decreases inflammation in vivo following alkali injury." Experimental Eye Research, 84(2), 278-286. [Online].
Available: https://pubmed.ncbi.nlm.nih.gov/17094961/
Xiong, Y., et al. (2012). "Neuroprotective and neurorestorative effects of thymosin β4 treatment following experimental traumatic brain injury." Annals of the New York Academy of Sciences, 1270, 51-58. [Online].
Available: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547647/
Su, L., et al. (2022). "Thymosin beta-4 improves endothelial function and reparative potency of diabetic endothelial cells differentiated from patient induced pluripotent stem cells." Stem Cell Research & Therapy, 13(1), 13. [Online].
Available:https://stemcellres.biomedcentral.com/articles/10.1186/s13287-021-02687-x
Stark, C., et al. (2016). "Thymosin beta 4 treatment improves left ventricular function after myocardial infarction and is related to up-regulation of chitinase 3-like-1 in mice." Translational Medicine Communications, 1, 8. [Online].
Available: https://transmedcomms.biomedcentral.com/articles/10.1186/s41231-016-0008-y
Crockford, D., et al. (2010). "Thymosin β4: structure, function, and biological properties supporting current and future clinical applications." Annals of the New York Academy of Sciences, 1194, 179-189. [Online].
Available: https://pubmed.ncbi.nlm.nih.gov/20536467/
Bock-Marquette, I., et al. (2004). "Thymosin β4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair." Nature, 432(7016), 466-472. [Online].
Available:https://pubmed.ncbi.nlm.nih.gov/15565145/

TB-500 (Thymosin Beta-4) represents a promising avenue for various therapeutic applications, particularly in tissue repair, cardioprotection, and neuroprotection. As with all research peptides, it is important to use TB-500 in controlled research settings, and its potential benefits and risks require further scientific scrutiny before any clinical applications can be considered.

TB-500 (Thymosin Beta-4) 10MG

Product Usage

What Is TB-500 (Thymosin Beta-4) 10MG?

Structure

Research Findings

Future Research Directions

References

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