Melanotan 2 10MG

Melanotan-2 is a synthetic analogue of alpha-melanocyte-stimulating hormone. It enhances skin pigmentation, boosts sexual arousal, and may reduce compulsive behaviors. It’s popular for its tanning effects

Product Usage

This product is designated as a "Novelty Peptide" and is intended solely for specialized applications in controlled settings. It is not intended for any specific biological, therapeutic, or diagnostic use. All information provided on this website is for informational and educational purposes only and should not be construed as guidance for any particular application or usage.

What Is Melanotan 2 10MG?

Melanotan II (MT-II) is a synthetic analog of the peptide hormone alpha-melanocyte-stimulating hormone (α-MSH). It functions as a non-selective agonist of melanocortin receptors, primarily targeting MC1R, MC3R, MC4R, and MC5R. Originally developed as a potential treatment for sexual dysfunction and as a tanning agent, Melanotan II has gained attention for its effects on skin pigmentation, sexual arousal, and appetite suppression. However, it is not approved for medical use in most countries and is considered an unregulated substance.

Structure

Research Findings

Skin Tanning: Melanotan II stimulates melanogenesis, leading to increased skin pigmentation without sun exposure. This effect is primarily mediated through MC1R activation.
Sexual Function: Studies have shown that Melanotan II can induce penile erections in men and increase sexual arousal in both men and women, likely through MC4R activation.
Appetite Suppression: Melanotan II has been observed to reduce appetite, potentially through its action on MC4R in the hypothalamus.
Pigmented Lesions: There are concerns that Melanotan II use may lead to changes in existing moles and the development of new pigmented lesions, potentially increasing melanoma risk.
Cardiovascular Effects: Some studies have reported changes in blood pressure and heart rate associated with Melanotan II use.

Future Research Directions

Long-term Safety: Extended studies are needed to evaluate the long-term effects and safety profile of Melanotan II, particularly regarding its potential carcinogenic effects.
Mechanism of Action: Further research is required to fully elucidate the molecular mechanisms by which Melanotan II exerts its diverse effects across different tissue types.
Therapeutic Applications: Investigation into potential medical uses of Melanotan II or its derivatives, particularly in the treatment of sexual dysfunction or pigmentation disorders, while addressing safety concerns.
Drug Interactions: Studies on potential interactions between Melanotan II and other medications or supplements are warranted.
Delivery Methods: Research into alternative delivery methods that could improve safety and efficacy profiles.

References

Brennan, R., et al. (2017). "Melanotan II: acts at melanocortin receptors MC1R, MC3R, MC4R and MC5R to induce skin tanning and suppress appetite." Pharmacology & Therapeutics, 177, 56-65. [Online].
Available: https://pubmed.ncbi.nlm.nih.gov/28223234/
Langan, E. A., et al. (2010). "Melanotan: a potential new treatment for resistant acne?" British Journal of Dermatology, 163(4), 886-887. [Online].
Available: https://pubmed.ncbi.nlm.nih.gov/20854435/
Hadley, M. E., et al. (2006). "Discovery and development of novel melanogenic drugs. Melanotan-I and -II." Pharmaceutical Biotechnology, 329-360. [Online].
Available: https://pubmed.ncbi.nlm.nih.gov/16399414/
Dorr, R. T., et al. (1996). "Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study." Life Sciences, 58(20), 1777-1784. [Online].
Available: https://pubmed.ncbi.nlm.nih.gov/8637402/
Nelson, M. E., et al. (2019). "Melanotan II non-selectively masks benign and malignant pigmented skin lesions." Australasian Journal of Dermatology, 60(4), 315-317. [Online].
Available: https://pubmed.ncbi.nlm.nih.gov/31168823/

Melanotan II represents a potent synthetic melanocortin receptor agonist with diverse physiological effects. While it has shown potential in areas such as skin tanning and sexual function enhancement, its use remains controversial due to safety concerns and lack of regulatory approval. As with all unregulated substances, it is important to approach Melanotan II with caution, and its potential benefits and risks require further scientific scrutiny before any clinical applications can be considered.

Melanotan 2 10MG

Product Usage

What Is Melanotan 2 10MG?

Structure

Research Findings

Future Research Directions

References

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